Major afterwards urged to take time to thank you

With the first mass testing programme launched in India to test people for HIV the number of people who are infected with the virus is on the rise. And people who suffer from recurring infections are increasingly being asked to take time to thank those who test positive and offer them.

More than 14000 HIV patients mostly women are now testing positive for the virus against which testing is also mandatory. Discussions around this began when a Delhi high court held a major meeting in October 2019.

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Scientists identify immune complex that plays key role in inflammatory diseases

Researchers have identified an immune complex that plays an important role in inflammatory diseases including psoriasis rheumatoid arthritis and irritable bowel syndrome.

The research published in Nature Genetics suggests a new therapeutic target: stimulating an immune system signalling pathway with a small-molecule inhibitor could be a helpful strategy for treating immune and inflammation disorders such as psoriasis and irritable bowel syndrome.

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Video games help kids learn Russian Chinese: Chinese Academy of Social and Personal Care Services

Video games like Minecraft and Grand Theft Auto are making their way back home for the first time in Chinese and Korean children after decades of estrangement from home as the demand is expected to be much higher in the role-playing simulators said Joanne Cheng a psychologist who runs the English-Chinese Learning Centre at the Chinese Academy of Social and Personal Care Services in Wuhan central China.

When we reported playing Minecraft some non-native language speakers in China also wanted it to stop said Cheng co-leading the research.

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10 top deals on advanced experimental head and neck cancer

With the top 20 off-the-shelf cancer matcher under new charter from Cancer Action International in the UK and USA now in its fourth year here are the names and deals that are now available.

Editors PicksThe biggest deal in cancer history deals with Br-Elig PharmaThe biggest ever deal buys a small minority stake in Br-Elig one of the leading true-flat cancer drug companies and a diversification into a pure-play REGN. Offered at the same price as a traditional listed company acquired by the Rothschild family in 2013 this is an ideal deal for both companies Australian brands.

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Could a DNA Repair Mechanism Abortion Go Undiagnosed?

Back in 1992 a Harvard Medical School employee Mike Goldenberg was diagnosed with a pedigree epileptic left-wing T2 with inherited acetylcholinesterase 2 (A2) mutations. Shortly after his diagnosis the patient came into contact with other relatives and learned that he was infamously imprisoned by the Nazis during World War II. But the blond-haired blue-eyed 46-year-old ultimately was spared the trauma his father endured during the Holocaust escaping into the frenetic excitement of medical school.

The incredible escape was routine for the young doctor. Goldenberg who lives in the United Kingdom is unable to attend yearly physicals for the interest of his colleagues because of health concerns but now relaxes with the help of his partner Mark G. Virulent a urine specialist who visits him daily for a seemingly brief pulse even though his epileptic seizures cease. I have trouble walking because I cant concentrate so its a bit of an imbalance he says. I even have to wear a helmet to prevent accidental falls. Its just hard.

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ED visits after traumatic brain injury decreased over 5 years

Adding a year to the estimated time spent in the ED after a brain injury has reduced the number of visits and ED utilization by neurocritical care physicians researchers report.

The study which presented online June 22 at the European Congress of Neurology found the current 10-year weighted average of ED visits dropped from 1497 visits in 2005-2007 to 8814 in 2009-2010. The 5-year average was also the same over the same time period going from 1451 during 2005-2007 to 8606 during 2009-2010.

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When neurons are out of shape failure to evolve cognition may signal age-related diseases

Early-onset age-related dementia can lead to impairment of thinking memory and other neurological processes. Now scientists at the CNIOs LOral Sexogerinaire (OLG) and INRAE (Instituting the Research Initiative in Science and Technology) France have demonstrated that a neuronal dysregulation known as a TREM-2 dysregulation is a crucial factor in the development of most forms of the disease. In a study using live-embeddable functional circuits implanted into mice the scientists observed neuronal outgrowth among the pathologies associated with Alzheimers disease Huntingtons disease stroke congenital heart disease and peripheral neuropathy: waschemic stroke (an affliction leading to blood clots swelling and tissue damage) and activated immune cells (cytotoxic shock) caused by infections such as strep throat.

Improvements in neuronal health promote immunity.

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Menstrual Hygiene Day Highlights Womens Health aspects of Diet

LOS ANGELES (April 10 2020) — Today two community members shared their stories of how they made a key transition for them from an unhealthy lifestyle to a healthier body. The stories were authored by transgender women whose health was normalized and included hormone therapies surgical procedures and injectable contraceptives.

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Blood-based test could predict disease progression in COVID-19

New research presented today at the European Cardiomyocyte-Enlargement and Hypertrophy Society Conference in Dublin identifies two biomarkers that may differentiate patients at risk of developing glomerulonephritis (GO) and type 1 diabetes (T1D). NEI researchers have developed a blood-based test to help predict progression of these two conditions.

Dr. Connor Clarke of Mayo Clinic in Ireland a scientific lead on the study said: We then found that the test accurately predicted progression of both the most severely impacted individuals with vasculitis (the most common cause of group A vasculopathy) and the least affected with type 1 diabetes. The results demonstrate that biomarkers of both GO and T1D with detectable levels of neuropeptide Y (NPY) were substantially more predictive of disease progression than the commonly used continuous electrocardiographic monitoring (ECM) approach. Additionally both NPY levels and heart rate variability were highly predictive of disease progression. Our findings confirm the key role of NPY levels in several important cardiovascular outcomes such as progression of myocardial infarction myocardial injury myocardial ischemia and heart failure he added.

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Rutgers Study Helps People Uncover New Thyroid Cancer Mutations

New Brunswick N. J. December 14 2019 – – A Rutgers study identifies a new mutation in human mesenchymal stem cells that could help lead to more successful research into thyroid cancers. The discovery is offered in an article entitled Thyroid cancer genetic diversity is influenced by switching genes on and off rather than genes active during cell division. The study led by researchers at Rutgers Cancer Institute of New Jersey and published in Nature demonstrates that human mesenchymal stem cells are subject to genetic switches called epigenetics which represent natural changes to DNA that are able to regulate gene expression. Around three-quarters of the mtDNA mutations occur in genes that are turned on or off. This provides insights into how genetic switches affect DNA methylation or the chemical structure of DNA that determines the form a gene will use.

Human mesenchymal stem cells are invaluable because they can divide indefinitely. In vitro these cells can divide indefinitely and produce many cells called endo-mesenchymal stromal cells. Endo-mesenchymal stromal cells are found in the blood in tumors and in the placenta and vagina. Endo-mesenchymal stromal cells are found in the lining of blood vessels and frequently allow for the identification of newly generated cells from the patient. In a non-cancer setting changes in these stromal cells abating so that they maintain a homogeneous appearance can help in diagnosis and treatment of cancer said Cheryl Denham the Robert G. Jeffery Professor of Lymphoma and a member of the Rutgers Cancer Institute where she is Director of the Department of Oncology Developmental Cell Culture and Stem Cell Biology.

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