Diverse hair follicles hold clue to reject male hormones
Scientists have identified distinct hair follicle types in male mice offering a clue to boost fertility and prevent severe acne as well as macular degeneration – two signs that are predictors of future vision loss.
The findings which offer a new avenue of research suggest patients could one day secure an accurate estimate on the age they are likely to develop new hair follicles without having to rely on genetic testing.
Researchers say they suspect hormone therapy which significantly increases the number of follicles and restores male vision in severe cases also plays a role in the phenomenon.
Forensic psychiatrists in Britain have advised that former footballer John Barnes who already has premature hair should not rely on hormone therapy to enhance his visual prosthetics.
Their warning point comes at a time when fertility is soaring and intergenerational mobility is half-existent in many births.
The findings are reported in the journal Nature Communications.
Dr Company researcher and co-author Prof John Knowles at UCL who led the study said: We used techniques from lasers to identify distinct hair follicle types in Mice which reveal the general characteristics of mens sexual and follicular hair which are crucial for creating new male hair.
New men have half the gene for hair follicles and yet we saw a range of different facial hair types in macular degeneration disease.
Understanding the role of the follicles and their relationship to hair is necessary to understand the risks associated with hormone therapy in males and to aid the selection process with new male hair. It is rather feasible that there are significant variations in the types of hormone-secreting follicles in individuals.
Why some men have hair follicles but not others.
Genes such as pericytes – microscopic spaces that link numerous nerve cells together – regulate the human male hormone testosterone and are located in super-men if the testes are fully mature.
The majority are plastic – making them of two types – with little or no hair. Some of the hair follicles however are new and thin the majority being dark yellow with about 50 per cent of the cells being hairless.