Benefits of ancient herbal medicine get livers rewired

The number of patients affected by liver diseases is increasing year after year yet its not clear where to target those patients for treatment research shows.

There are estimated to be about 164-175 million people living with nonalcoholic fatty liver disease or NAFLD (NAFLD is a combination of metabolic and digestive issues that can lead to liver failure and liver cancer). Currently no treatment exists for patients who have discovered theyre carrying excess WHM and WHT protein but are unresponsive to current-like therapies.

A study conducted by researchers at Cedars-Sinai Medical Center in Los Angeles found that long-term treatment with ancient herbal medicine can substantially reduce hepatic cancer cell activation and increase the mitochondrias ability to perform efficiently.

In addition the findings suggest that ancient herbal medicine may also be used to successfully treat ovarian cancer and pancreatic tumors.

The findings published today in the New England Journal of Medicine provide first evidence of the therapeutic efficacy of ancient herbal medicine.

We believe these studies will come into play for guiding medical and scientific decision making for patients over the coming years said lead author Seiko Kurotani MD PhD Director of the India Program in Human Nutrition and Dr. Cheng Zhang Professor CFTREVM and Bl Golden Institute for Translational Sciences (BITC). Dr. Kurotani disclosed the study grants from San Diegobased commercial affiliates of Daiichi Sankyo Co. Ltd. Takeda Pharmaceutical Co. Ltd. and Teich Society for Diabetes Research.

They conducted the scientific study of 81 patients half of whom were receiving targeted treatments including a calcium channel blocker and cardiovascular shock (CVOT). The researchers were surprised to find no detrimental side effects from these therapies in patients who did not self-administer the drugs. But in those who did the measured levels of tumor lysis enzymes (TLS) which produce and release molecules that drive cell death markers of inflammation and blood glucose and other broken down products disappeared. Across the group the BST enzyme which metabolizes sulfur compounds (metabolites of sulfur and oxygen in organisms) decreased to near-normal levels and activity in response to the targeted therapies according to the study results.

The study also found that the medicinal compounds (plant-derived alkaloids). Both have antioxidant and antifungal properties despite their other questionable safety hypotheses singly or together they are poorly absorbed they may contribute to kidney injury and anti-free radicals may cause oxidative damage in cells undergoing cancer.

We were excited to publish our studies here to guide the research in patients with incurable or non-responsive NAFLD. Some researchers have incorrectly suggested that traditional herbal medicine in response to liver disease leads to beneficial liver function Dr. Kurotani said. Hopefully this data will allow us to support the development of best practices aimed at reducing your risk of serious liver failure.

Co-authors were Franois Bannon MD Choloma Regional Hospital Chulalongkorn Thailand; Mark Poole MD Kenwood Medical Center Bath MA and Tams Kakisti MSc Center QOV Research Institute The Travassores State University of Wrzburg Graz Austria; and Antonio Ifto MD Choloma Regional Hospital Chulalongkorn Thailand.

The research did not involve patients treated with other compounds as opposed to those who were treated with a single therapeutical agent (APS) or molecular inhibitors (a total of 11). Dr. Hank Sinusar MD MS from Cedars-Sinai Medical Center Los Angeles and Richard Massan PhD from the University of Texas MD Anderson Cancer Center Houston co-authored the article entitled Vascular Pharmacokinetics of Ayurvedic and Traditional Red Oils Presented with Lonerganic Anticoagulation. The articles were published in the New England Journal of Medicine.