An engineering technique could revolutionize cancer treatment and biotherapy

Todd Frazier an MDPhD candidate in Baldwin-Cooks University of Alabama at Birminghams Department of Mechanical and Aerospace Engineering has been awarded a Breakthrough Prize in Scientists for Design of Health Systems which is celebrating its 10th anniversary. This is the first new award for tuberculosis (TB) which has received the Breakthrough Prize since it was created in 2008.

Dr. Frazier and her research team are using custom integrated circuits (ICC) technology simple cell manganese nanoparticles and simple fiber electronics to create a new family of drugs for TB. Their purpose is to deliver new medicines that develop effective TB treatments in the body. The treatment involves stop growth or TB drug transport an approved medication or a combination thereof. The TB-T panel treatment uses sound technology to deliver a controlled flow of sound waves centered on the point of amplification.

The award of this Prize is for designing an inflatable inflatable platform – simple implantation of sound and biolabial plexus membrane microfluidics systems within the bodys head to deliver TB treatments for treatment. Breast cancer is the most aggressive type of cancer. Patients are often limited to weeks-long infusions due to TB-associated resistance that increases symptoms infects other body organs and increases the need to readjust therapy regimens over time. After almost every patient is treated many succumb to the disease.

The Breakthrough Prize goal is to create this new technology as a means to treat a wider variety of diseases including diabetes and cancer. Currently most therapies simply target the bacteria containing the TB infection. However it is becoming obvious that many TB patients are resistant to multiple antimalarial drugs including methacrylamide and famotidine which are widely available in Europe and are relatively safe and effective. As a result there is a need for treatments that can simultaneously treat the bacteria and the salt containing the TB toxin.