Mount Sinai and York University study finds unlikely molecular link in common immune cell of skiers and skiers-race

Using a variety of breathtaking mountain equipment scientists for the first time have been able to analyze immune cells from three skier and four ski jumpers-from young to old-and have hit the definitive same-sex dino-hair experiment on both groups. Findings were recently published in the Journal of Sports Medicine Science in Action.

We have been meditating in the midst of intense experiences chug closer to the girls themselves to ask: What am I doing right now? said McKeihan a professor of immunobiology and immunology at Mount Sinai the fabled Venetian resort where Snowmass skied in the 60s. Im observing the immune responses of my fellow skiers. And this discovery may point to something not only in their hormones but also their physical anatomy. There was something it-or because of it-might be affecting them.

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Chemical compound may help treat chemotherapy-resistant prostate cancer

The chemical compound niveluromethine may help treat cancer patients who are chemotherapy-resistant according to a preliminary estimate of the drugs effect on the growth of a type of common early stage prostate cancer.

There is no approved topical medication for cancer and the effect of niveluromethine on growth and spread of prostate cancer in the subset of patients with advanced lymphoblastic leukemia (CL) has not yet been determined said Kristin DArousa Acting Director of the Markland Cancer Center at the University of Pittsburgh. Comprehensive studies are needed to confirm niveluromethines effectiveness and safety and if needed may even be extended beyond the dosage that is already in use she said in an interview with Medscape Medical News.

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New study shows that glucose triggers protein that promotes cancer

In a new study a group of researchers from the University of Tel Aviv Israels top genomic health institute TAUs Sackler Faculty of Medicine and Aalto University have shown that despite its name glucose triggers a protein highly likely to make cancer spread or metastasize. Researchers also found that the proteins molecular interactions with genes involved in cancer stem cell development may be helpful in understanding specific interactions of the protein with cancer cells thereby helping in future research.

The protein known as Klu-1 activates genes associated with cell division and induced cell proliferation making it a highly-readily involved protein in cancer until now. In the current study researchers investigated whether the protein which is packaged inside a elongated protein called Klu-FGB1 had even more specific tissue-specific functions involved in the formation of cancer stem cells. They discovered that this protein significantly increased the blood-brain barrier bone marrow production (exercise-dependent stem cell differentiation) and circulating tumor levels of C-reactive protein a key biomarker for cancer spread or metastasis.

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Scientists identify gene essential for normal liver metabolism

As obesity increases a growing need for fat in the body becomes more of an issue. As people become overweight and obese they are at greater risk of developing diabetes insulin resistance and liver failure. But it is still unclear why these diseases develop at the same time that the liver becomes thinner. Researchers at Karolinska Institutet in Sweden have now found a possible answer: genes that are essential for the healthy liver metabolism. The study is published in the journal Cell Metabolism.

Liver fatty liver disease is a common problem that has been seen in different ethnic groups and can present suddenly after a few weeks living with a low-fat diet. Scientists do not yet understand the exact relationship between obesity and liver fat but they do know that the fat in the liver is not transferred from the fat tissue to the bloodstream and therefore fat in the liver is not only the source of unpleasant or unpleasant effects but also a major cause of obesity-related diseases.

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Study evidence of link between draconian malaria control measures and reduced disease transmission

A study by researchers in Guinea Sierra Leone and Liberia has identified a link between draconian malaria control measures in Southeast Asia and reduced malaria transmission between endemic and non-endemic countries. According to the study by the International Malaria Research and Action Programme (IMRAP) the results support the need for more stringent control measures across the region.

The study consisting of actions by governors villages and municipalities government officials and international partners in Myanmar Cambodia Honduras Pakistan and the Philippines covers an area area of two billion people and 10 years: southern Africa Central Africa the southeastern part of sub-Saharan Africa and the Indian subcontinent.

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Malaria breakthrough clears path for novel CBD drug

CAR T cells a promising new class of cancer immunotherapy drugs for the first time will not need to pass through the blood-brain barrier (BBB) to reach the tumor site. That achievement from a team led by investigators in the Abramson Cancer Center at the University of Pennsylvania Harvard Medical Schools BRAIN Institute and Penns Alzheimers and Dementia Center opens a pathway for clinical research to focus on this new pharmaceutical.

Cell-based immunotherapy is a form of cancer immunotherapy that uses patients own immune cells to attack their tumor. Many types of cancer have successfully reprogrammed immune cells to target tumor cells where the cells proliferate and heal. There is a marked need for additional treatments that bypass the blood-brain barrier preventing treatments from reaching the tumor site other treatments such as targeted therapies which are currently limited by a BBB receptor size of 5-10 nanograms per milliliter of blood for patients with small or mutable solid tumors.

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Black patients more likely to develop AIDS

African-American gay and bisexual men are more likely than heterosexual men to develop severe HIV and some African-Americans have high rates of HIV according to a report released today by the Vincent N. Tobin Centre for AIDS Research Dept. of Health University of Liverpool.

Vincent N. Tobin Centre for AIDS Research University of Liverpool said that the study highlighted an opportunistic bias in sexual minority communities with the study suggesting that heterosexuals might be expected to demonstrate a cooperative attitude towards non-HIV infection while homosexuals might show a negative attitude. Furthermore using a questionnaire to measure HIV transmission the researchers reported that almost two-thirds of self-identified African-American men and nearly half of heterosexual men and

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Genetic study reveals how common tumor suppressor gene affects cancer progression

A UCLA-led genetic study suggests Gene2. 0 (MITF2) can be a driver of tumor progression and extended survival in several common types of cancer. The study could advance the ability to identify genotypephenotype differences that impact clinical outcomes and enable targeted drug development.

Results of the Duke Cancer Institutes 150th Annual Meeting were published in Cell Reports Neuroscience and presented at the 60th Annual Meeting in San Diego.

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Experimental drug effectively slows spread of aggressive breast cancer

A promising drug candidate can douse kill and curb dormant and treat high-grade breast cancer cells.

Harvard scientists in collaboration with Beth Israel Deaconess Medical Center have found a way to switch key genes off in multiple forms of breast cancer cells addressing the enormous resistance plaguing the disease. The approach which they anticipate will be used in a number of other types of breast cancer could significantly ameliorate drug-resistance. The study which will be presented at the American Society for Metabolic and Bariatric Surgery (ASMB) 68th Annual Meeting in Philadelphia March 4-9 appears in Metabolism.

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