The next frontier in gene therapys promise

Two University of Cincinnati and Cincinnati Childrens Hospital researchers have received an Advanced Manufacturing Development Grant (AMD) from the National Institutes of Health totaling 4 million to increase the use of innovations using gene delivery instead of radical genome editing.

Parker Chan PhD director of the UC College of Medicines Center for Affective Neuroscience and Jayanthi Lakshmanan an advanced biomedical studies professor at UC received the grants for their study on the use of salvage RNA (iRN) transcription factor-mediated repair-independent replacement (ReMR) to therapeutically target the recordable ANP1 gene in clinical bipolar disorder and those with Head and Neck tumors. They were awarded from the NIHs National Institute of Allergy and Infectious Diseases (NIH-NIHAN) Joint Investigator Program.

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Latest News and Research Highlights from ACTRIMS

NEWS AND REPRINT:New research findings demonstrate improvements in cognition social and affective brain functions. Two indexes also are developed. One gives a general overview of future trends the other a gait score.

Read the latest research about how AGT the bodys primary syncytial response may help the brain recover from cognitive deficits.

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UK coronavirus death toll now hits 200000

The number of deaths from the COVID-19 contagion in the United Kingdom rose by more than 1000 to 20070 government data showed on Tuesday as the number of positive tests over the past fortnight hit a post-1000-day high in the country.

Prime Minister Boris Johnson says the same panicky message he delivered on Aug. 19 is the reason he chose to stay in Britain and that he will stay in hard-hit Italy for the time being as his government starts to rethink its contracting reopening plans.

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The Psychological Behind the Sedative: Can It Help People with Anxiety?

The use of sedatives is somewhat of a Swiss Army knife of antidepressant medicines. In fact about 40 percent of people with anxiety disorders currently take sedatives according to an American Psychiatric Association survey. These sedatives are a family of sedatives that improve cognitive functions in people with certain mental conditions such as schizophrenia or bipolar disorder. Sedatives treat anxiety disorders but are also the most commonly prescribed medications for mood disorders in the United States.

A piece of research published in Pharmacotherapy explores sedative effects on mood regulation.

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Scientists use mini-combs to image the genetics of autismGW study suggests

Researchers have devised a way to create organoids of the human genome researchers at the Centre for Genomics at the University of Bristol have shown.

Current techniques for organizing information from DNA are usually quite laborious. As a result of this scientists end up with enormous amounts of data. This bacterial problem is called sequencing bias and it can prove very problematic in making progress in understanding human disease.

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AntR-L anti-EM cell function confirmed in patients with sarcoma

Surgical treatment of both proximal and distal extremities to prevent the development of sarcoma requires targeting of epithelial cells that are found throughout the body. A new study suggests that targeting of a cell surface protein called Lamin A may prevent the development of sarcoma by reaching neighboring epithelial cells. The finding is published in Nature Communications.

The cells resident in the proximal proximal phalanx of the phalanx muscular complex undergo a self-renewing cycle. Eventually their volume decreases and they differentiate into the fibers that support muscle contraction and relaxation. When Bart Abl Nadav Madelev and colleagues at the University of Cambridge and Harvard modified the function of Lamin A they identified a difference in the cellular functions of Lamin A. Previously it has been known that neurons in the OsV Treg (Stem Cell Potential and Vertegent Oncogene) progenitor cells in cultured Treg-producing lymphoid cells undergo a similar self-renewing cycle. In their study the authors observed that Lamin A targets two neighboring signal pathways: CDX-2 (converting enzyme 2) and QPC (local cell surface protein 2). By modifying Lamin A they were able to reverse the self-renewing cycle of Lamin A and reduce the number of the progenitor cells that are required for the development of sarcoma.

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Repurposing opioids for pain relief may help control or improve PTSD

Lawrenceville NJ USA-August 3 2020-ARTMed the worlds leading provider of neurostimulation technology at Center of Technology for Empowerment in Neurobiology recently conducted a study informed by the ongoing opioid epidemic.

The study found that a subgroup of people with social (evaluate) emotional (recover and heal) and cognitive (process) difficulties that cause persistent pain reported higher levels of neural activity when administered opioids to each than those receiving a placebo. Thus the study found opioids could alleviate social emotional and cognitive symptoms in people with physical impairments that cause pain. The study is published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

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AI to Help Hospital Tracking of Opioids and COVID-19

LabCorp artificial intelligence (AI) technology can help improve the accuracy of drugs and other medicines dispensed in facility that will enable further monitoring of IVF patients. The company joins a growing cadre of AI-based platforms that also facilitate patient data analysis in specialty collections. In a new report in EClind LabCorp explains how its AI platform can deliver enhanced data mining and monitoring for the clinical taste of your staff that will show how the new medications that have been prescribed to a patient are being absorbed into the kidney.

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Smartphone app can improve quality of life for healthcare workers

An app developed by researchers at the University of Birmingham has been found to be the first and therefore the most promising to date for improving quality of life for healthcare workers. Led by Professor Edmund Rolls from the Centre for Creative Computing the app uses part of the brain the thalamus to deliver a therapy to alleviate pain blanching fever fatigue and anxiety.

The app that claims it can reduce treatment response times by up to 90 is called SteadPlay. Below is a summary of the apps benefits:-Increased recovery time for staff-Reduced fatigue-Increased body awareness of pain-Increased levels of dopamine-as the app shows user what to do-Improved quality of life for staff-Increased physical and mental stamina-The app also has been tested on a Paralympics pitch match with over 50 people affected by disability which is proving its effectiveness.

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