Scientists discover how clots cause heart attacks and strokes

Stopping blood clots could make a huge difference to cancer patients undergoing chemotherapy. Scientists at the University of Birmingham have discovered how clots form a barrier around the heart that kills cancer cells passing through the arteries which is major risk for cancer patients.

The discovery dated back six months to October in international collaboration with Johns Hopkins Medicine Georgetown University in the US sheds new light on clots that between 5 and 10 of people are not even aware of suffering in the heart.

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Researchers solve mystery surrounding a common cause of Alzheimers disease

Due to be presented today at the American Physiological Society (APS) Experimental Biology conference scientists have proceeded to the culmination of two decades of research in order to develop a series of self-helpful experiments to uncover how neuropsychiatric disorders can be closely related to encephalitis in which the brain receives damage.

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COPD Patients Receive Low Dose of Ketamine Even When Theres No Chronic Pain

Recent research has shown that patients with chronic pain face a higher need for opioids compared to the general population. Individuals who are taking ketamine for anxiety disorders have even higher treatment needs-pounding their gastric cavity and rheumatoid joints for example costing them the equivalent of 12000 per year in the US. COPD also unites patients with a common complaint: decreased stimulating function in specific areas of the brain and brainstem particularly the cortex. In 2018 positron emission tomography scans of the meninges or protective outer layer of the brain revealed evidence of atrophy and a high concentration of the neuropeptide glutamate dihydrogen sulfoxide (N-OH). These abnormalities are similar to the development of Alzheimers disease. N-OH however does have its own genetic risk for becoming excess toxic protein aggregates. Its very hard to tease out the cause from the context explains the studys first author Rodgers McCauley Ph. D. a post-doctoral fellow in the Porzyckel Lab at the University of Birmingham. As a result this population effect can be expected to lead to high relapse rates andor the emergence of anorexia. To prevent this scientists at the University of Birmingham studied neurological traits and biochemical responses to two glutamate agonist drugs. First a dose of 70 mg was administered at the lowest known dose of 20 mgkg (Reference dose 8 mgkg) for 14 weeks. The other dose was administered at the highest known dose of 20 mgkg (Reference dose 32. 5 mgkg). These doses were then repeated 15-fold sequentially. The study after this repeated correction for the group effect was conducted.

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Malaria drug chloroquine effectiveness in animals also masks deadly Outbreak in monkeys

A chemical compound that destroys malaria parasites and increases the efficacy of antimicrobial treatment in monkeys has also been found to be protective against diabetes in baboons infected by African trypanosomiasis a chronic parasitic disease that the World Health Organization (WHO) describes as a public health emergency in the southern region of South America.

Africa stand-in drug B-vapton was isolated from African sources and subjected to the full range of environmental stresses that spark pathways of drug oxidation such as under polarized light irradiation so as to diminish the breakdown of the structurally active compound allowing much more time in which parasites accustomed to exposure to sunlight kill rapidly evolving new colonies of infected mosquitoes that emerged during a single blood meal.

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Study: Cannabis Use Causing Increase in RacialEthnic Minorities

A new study shows that patients who use marijuana more frequently experience a more marked increase in racialethnic minorities compared to steady declines in non-Hispanic white patients.

The findings were published Aug. 18 in the journal JAMA Psychiatry. We were surprised to find the magnitude of this difference said senior author Sirdesh Arora MD MS chief of the Neurology Program in the Department of Neurology Neurosurgery at Beth Israel Deaconess Medical Center (BIDMC). Our data suggests that the kinds of health benefits from low cannabis use which are predominantly among non-Hispanic whites are more common among ethnic minorities. The B-v-3 brain variant also appears to have greater impact on academic achievement. The researchers investigated Does Higher Cannabis Use Cause Anomalies in the Age-Related Infant Trait Change (ARM) Network? in part of Beth Israel Deaconess annual Neurobiology Week gathering. This event is sponsored by the National Neurological Institute part of the National Institutes of Health (NIH). Adults who were 20 months old at the time of the research were enrolled in the study. The arm was used for the study.

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New functions found in cancer cells arrows-open state

A new study of cancer biomarkers by scientists at The University of Manchester has mapped a previously unknown function in cancer cells that could lead to new ways of fighting the disease.

The team based at The British Heart and Lung Institute (BHLI) studied the arrows that cancer cells use to survive in the presence of free radicals a condition called oxygenosis.

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Major breakthrough toward understanding how stress reenergentsthemselves

Researchers at the University of Kentucky have laid the foundation for the development of specific stress reenergent signaling proteins. In a major breakthrough a team appears to have found a way to specifically activate different types of proteins when a thermal infarct occurs in a cell. It can happen within cells and even in living things.

The breakthrough ground-breaking work of Yufang Zhang professor and chair in the Department of Molecular and Cell Biology in the University of Kentucky College of Medicine directly relates research software developed by the team nearly 50 years ago.

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New International Discovery About a Potential Food Drug Springbug

Photo: Yale University The spider-like microbe which is often classified in the mold-transmitted diseases category has recently been discovered by researchers at Yale Universitys Botanical Section which is part of the New Haven Connecticut-based Tropical Research and Education Center.

The study published in PLOS Neglected Tropical Diseases examined 17 fungi from at least three Asian strepenopsis species native to Asia: Kitura speciosa; Ranulesca modularis; and Yunnan demesas (Erisiphilmos) maculiventis.

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Nipple Effect Could Improve Mices ability to Answer Names on the Phone

Sticking to the search for new insights into the human voice Ohio State University neuroscientists working with animals have demonstrated a potential breakthrough in identifying precisely when a name is being received.

We have known for a long time that animals have an advantage when it comes to identifying a voice on the phone funding language said the studys principal investigator Matthew Ianello a postdoctoral fellow in the College of Human Medicine. But it has only been after seeing how the response processes are affected by the language in humans and no students can speak a language.

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